Did you first learn about rabies through the children’s book or movie “Old Yeller”? Rabies has changed drastically over the last century in the United States, moving from a majority of cases occurring in domestic animals like the literary canine hero, to a disease occurring predominantly in wildlife. That makes rabies a significant wildlife management challenge in the U.S. today, and a reason the United States Department of Agriculture and our partners in rabies prevention and elimination recognize World Rabies Day on September 28, 2020. This is a day of global action that started in 2007 to raise awareness for rabies prevention and to enhance control efforts worldwide.